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Endothelial dysfunction is now regarded as an early marker of vascular disease and therefore an important target for therapeutic intervention and discovery of novel treatments. Ideal for both basic and clinical scientists, whether in industry or academia, and physicians, ‘Vascular Endothelium in Human Physiology and Pathophysiology’ provides an up-to-date review of the vascular functions of the endothelium and its role in key areas of cardiovascular disease. It focuses on evidence from studies in humans.