Livro online Tumor Angiogenesis And Microcirculation – Voest, Emile E. – ISBN: 0824702646 para você comprar em loja virtual. Confira preço, ofertas e descontos.
Compiling the latest developments in anticancer therapies based on the connection between tumor and capillary growth, ‘Tumor Angiogenesis and Microcirculation’ presents a comprehensive overview of diverse aspects of angiogenesis-related cancer research. Highlights the role angiogenesis and its inhibitors play in the growth, metastasis, and dormancy of tumors. Facilitating the progress of clinical practice with insights from methodological and scientific results, ‘Tumor Angiogenesis and Microcirculation’ – summarizes biological principles of angiogenesis and microcirculation, from endothelial cells and pericytes, and extracellular matrix regulation to matrix metalloproteinases (MMPs) and plasmin and plasmin inhibitors; examines proangiogenic factors such as vascular endothelial (VEGF) and basic fibroblast (bFGF) growth factors, tie receptors, and cytokines; outlines methods for discovering angiogenesis stimulators and inhibitor peptides, particularly the clinical development of thrombospondin, angiostatin, endostatin, and MMP inhibitors; reveals the link between oncogenes and neoplastic angiogenesis and its regulation by the organ microenvironment; investigates tumor vascularity in relation to tumor growth and the spread of cancer; details promising future applications, including perspectives in vascular cancer therapy and more.
Autor: Voest, Emile E.