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As cancer research increasingly becomes an applied science, academic and biotech researchers interested in general principles must think more about how their efforts translate into the clinical arena. At the same time, researchers on the industrial side stand to gain from a better understanding of the latest strategies for target and lead drug discovery. This way the great promise of new approaches to cancer drug development – preventions and treatments that will be less toxic and more effective than current drugs through targeting specific molecular features of aberrant cells – can finally be fulfilled. ‘Molecular Cancer Therapeutics – Strategies for Drug Discovery and Development’ offers an up-to-date overview of the different phases of drug discovery and preclinical development of new experimental cancer principles.