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Few cardiac disorders have generated as much controversy and discussion over the last two centuries as the floppy mitral valve (FMV)/ mitral valve proplapse (MVP)/ mitral valvular regurgitation (MVR) triad, and the mitral valve prolapse syndrome. During the past 50 years, recognition of its broad pathologic and clinical spectrum has led to the appreciation of the FMV as the central issue in the FMV/MVP/MVR story. Accordingly, the clinical phenomena and imaging characteristics inherent in the FMV/MVP/MVR triad will be best understood when reconciled with the gross morphologic, histopathologic, and molecular characteristics of the FMV complex. This book is written to cover the entire spectrum of FMV and its sequlae. The inheritance patterns, genetic studies, and development of family pedigrees.