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These volumes cover all relevant aspects of recent research in estrogens and antiestrogens from chemistry, physiology, pharmacology to clinical applications. Particular emphasis is devoted to new developments in the area of estrogen receptors including estrogen receptor ß and the mode of action of novel partial estrogen agonists/antagonists. Further topics address the importance of estrogen and anti- estrogens in fertility, aging, cancer, animal husbandry and environment. Part I discusses the complex chemistry of steroidal and non-steroidal estrogens and antiestrogens as well as the molecular mechanisms of estrogen action. Information is provided on the metabolism and the various physiological and pathophysiological responses of estrogens. The chapters have been written by experts in the field of endocrinology for researchers, lecturers, physicians and pharmacologists. Due to their broad scope these volumes will be indispensable reference books in any library.
Autor: Oettel, Michael