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Understanding the nature and role of endothelium-derived hyperpolarizing factor appears to be crucial in the quest for improved treatments for hypertension, diabetes, ischemia-reperfusion and other vascular disorders. ‘EDHF 2000’ comprises the proceedings of the Third International Symposium on endothelium-dependent hyperpolarizations. The first two meetings established a role for EDHF and other chemical factors involved in endothelium-dependent hyperpolarizations. These proceedings focus upon the role of gap junctions in cardiovascular responses and investigate the chemical identity of EDHF. Additional chapters on Physiology, Hormonal Modulation and Pathological Changes are also included.
Autor: Vanhoutte, Paul